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In the current review, we documented the identification as well as characterization of a brand new atypical opioid receptor with exceptional unfavorable regulatory Attributes in direction of opioid peptides.1 Our effects showed that ACKR3/CXCR7, hitherto referred to as an atypical scavenger receptor for chemokines CXCL12 and CXCL11, is likewise a w